Hand sanitizer in cold and flu season: at least 60% alcohol, rubbed in until dry, and soap first when you can
This time of year, a small bottle of hand sanitizer rides along in a lot of bags and cup holders. CDC says washing with soap and water is still the best way to get rid of germs in most situations. When soap and water aren’t available, it says to use a hand sanitizer with at least 60% alcohol, and to check the label to find out. [S1] [S2]
Our take: wash with soap and water when you can, for at least 20 seconds. When you can’t, use a sanitizer with at least 60% alcohol, cover every surface of both hands and rub until they’re dry. Skip it on visibly dirty or greasy hands, check any bottle against FDA’s do-not-use list, and keep it away from young kids and open flames. [S1] [S2] [S4] [S6]
Soap or sanitizer?
| Situation | Soap and water | Sanitizer, 60%+ alcohol |
|---|---|---|
| Hands look clean, no sink nearby | First choice | Use it if there’s no soap |
| Hands visibly dirty or greasy | First choice | Don’t use |
| Stomach bug going around the house | First choice | Less effective |
| After gardening or handling chemicals | First choice | Less effective |
| After the toilet or a diaper change | First choice | Use it if there’s no soap |
| No soap, but clean running water | Rinse and rub | Use it if there’s no soap |
On the label: at least 60% alcohol
Soap first
CDC’s view is simple: soap and water remove all types of germs from hands, while sanitizer kills certain germs on the skin. That’s why it calls handwashing the best way to get rid of germs in most situations, and sanitizer the backup when there’s no sink. [S1] [S3]
- Wet. Clean, running water, warm or cold. Turn off the tap and apply soap. [S2]
- Lather. Rub your hands together, including the backs, between your fingers and under your nails. [S2]
- Scrub for at least 20 seconds. Humming “Happy Birthday” from beginning to end twice is CDC’s timer. CDC says studies show 20 seconds is what it takes to remove harmful germs and chemicals. [S2] [S3]
- Rinse and dry. Rinse well under clean, running water, then dry with a clean towel or an air dryer. [S2]
CDC’s key times to wash include before, during and after preparing food, before eating, after using the toilet or changing a diaper, after blowing your nose, coughing or sneezing, after caring for someone sick with vomiting or diarrhea, and after touching an animal or garbage. Plain soap is fine: CDC says studies haven’t found an added health benefit from antibacterial soap outside health care settings. [S2] [S3]
Read the label
Hand sanitizers are regulated by FDA as over-the-counter drugs, so the bottle has a Drug Facts label. FDA says to read and follow it, especially the warnings section. [S4]
- At least 60% alcohol. CDC says you can tell whether a sanitizer has at least 60% alcohol by checking the label. [S1] [S2]
- Which alcohol. FDA names ethyl alcohol (ethanol) and isopropyl alcohol as the active ingredients these products should contain enough of. [S4]
- Alcohol-free bottles. CDC says sanitizers with at least 60% alcohol work against a wider range of germs than sanitizers without alcohol, including those that use benzalkonium chloride. CDC recommends the alcohol-based kind. [S3]
- Food look-alikes. FDA warns about sanitizers packaged to look like food or drinks, and found some with food flavors or fragrances, such as chocolate or raspberry. Swallowing them can cause serious injury or death. [S4]
- Homemade. CDC doesn’t recommend making your own. It notes reports of skin burns from homemade sanitizers, and says not to rely on recipes based only on essential oils. [S3]
How to use it
- Enough to cover. Put the product on the palm of one hand. Read the label for the right amount, and use enough to cover all surfaces of both hands. [S1]
- Every surface. Rub it all over, between your fingers and on the backs of your hands. [S4]
- Rub until dry. Keep rubbing your hands and fingers together until they’re dry. CDC says that should take around 20 seconds. [S1]
- Don’t wipe it off. CDC and FDA both say not to rinse or wipe sanitizer off before it’s dry, or it may not work as well against germs. [S1] [S4]
- Keep it out of your eyes. FDA says it can cause burning and damage. If it gets in, rinse thoroughly with water. [S4] [S5]
When it falls short
CDC lists the limits plainly. Sanitizer is quick, but it doesn’t do everything soap does. [S1] [S3]
- Visibly dirty or greasy hands. CDC says don’t use sanitizer then, for example after gardening, playing outdoors, fishing or camping. Wash with soap and water instead. [S1]
- Some germs. Sanitizers don’t get rid of all types of germs. CDC says soap and water work better against norovirus, Cryptosporidium and C. difficile. [S1]
- Chemicals. Sanitizer might not remove harmful chemicals such as pesticides, or heavy metals like lead. [S1]
- Wipes. CDC says hand sanitizing wipes with at least 60% alcohol kill germs on hands. Baby wipes don’t reliably remove germs, and disinfecting wipes are for surfaces, not skin. [S3]
- Water but no soap. CDC says to use a sanitizer with at least 60% alcohol. With no sanitizer either, rub your hands together under the water and dry them with a clean towel or let them air dry. That rinses off some germs, though it’s not as good as soap. [S3]
FDA’s do-not-use list
FDA says testing turned up some hand sanitizers that are contaminated with potentially toxic types of alcohol, don’t contain enough active ingredient, or carry false or unproven claims. It asks you to check its list before you buy a sanitizer or use one you already have. [S4]
The contaminants FDA has found include methanol (wood alcohol) and 1-propanol. In most cases, methanol doesn’t appear on the product label, which is why the label alone can’t clear a bottle. FDA lists methanol’s effects as including nausea, vomiting, headache, blurred vision, permanent blindness, seizures, coma, permanent nerve damage or death, and says young children who swallow these products are among those most at risk. [S7]
- Search with the label. FDA’s table can be searched by product or brand name, manufacturer, distributor or NDC (National Drug Code) number. [S6]
- Manufacturer missing. If the label doesn’t name the manufacturer, FDA says to contact the distributor to find out. If the distributor won’t say, FDA recommends you don’t use the product. [S6]
- Same brand, different maker. FDA notes that one brand name can be made by more than one manufacturer, so a warning about one maker doesn’t automatically cover everything under that brand. [S6]
- Problems. FDA asks people to report side effects from hand sanitizer to its MedWatch program. [S4]
Kids and pets
- Up and away. FDA says to store hand sanitizer out of children’s reach and sight, and out of reach of pets. Toddlers may be drawn to the pleasant smell or brightly colored bottles. [S4] [S5]
- Supervise. CDC and FDA both say adults should supervise young children using hand sanitizer, so they don’t swallow it. [S1] [S4]
- Small amounts matter. FDA says drinking even a small amount of hand sanitizer can cause alcohol poisoning in children. It also says there’s no need for concern if children eat with or lick their hands after using it. [S4]
- Dispensers. Wall dispensers are often at a small child’s eye level and can splash, so FDA says to watch young children around them. [S5]
- Pets. Don’t use hand sanitizer on pets or let them swallow it. If you think your pet ate something dangerous, FDA says to call your veterinarian or a pet poison control center right away. [S4]
Flames and vapors
- It’s flammable. FDA says to keep hand sanitizer away from heat and flames, and to rub your hands until they feel completely dry, with the vapors cleared, before anything involving heat, sparks, static electricity or open flames. That includes lighting a candle or the stove. [S4] [S5]
- Fresh air. FDA has warned that headache, nausea and dizziness can follow using alcohol-based sanitizer, likely from breathing the vapors in enclosed spaces. Use it where air moves. [S5]
- In the car. FDA says to open a window until the sanitizer is dry and the vapors have cleared. [S5]
Where the sources differ
Which alcohol at 60%: CDC’s pages say at least 60% alcohol, while FDA’s do-not-use page restates CDC’s advice as at least 60% ethanol. FDA’s consumer page names both ethyl and isopropyl alcohol as active ingredients. Our reading: look for at least 60% on the label with ethyl or isopropyl alcohol as the active ingredient. None of these pages gives a separate number for isopropyl. [S1] [S4] [S6]
How long to rub: CDC says rubbing until dry should take around 20 seconds. FDA ties the flame warning to hands that feel completely dry with the vapors cleared, and gives no time. Our reading: go by dry, not by the clock, especially near a stove or candle. [S1] [S4] [S5]
Children and swallowing: CDC says to supervise children to prevent swallowing alcohol, and FDA says licking hands after the sanitizer has been used is no cause for concern. These fit together: the risk is drinking from the bottle, not touching hands after use. [S1] [S4]
Health care settings: CDC recommends alcohol-based sanitizer as the main method for health care workers in most situations, but soap and water first in community settings. This guide follows the community advice. [S3]
Check a bottle
Pick what the label says. The check puts the CDC and FDA points from this page in one place. It can’t test what’s in the bottle, so FDA’s list is still the last step. [S1] [S3] [S4] [S6]
Choose the active ingredient to start.
If the check says the bottle looks fine, search FDA’s list with the product name, manufacturer, distributor or NDC number before you rely on it. Methanol usually isn’t on the label. [S6] [S7]
Before the next cold
Hand sanitizer check
If someone at home is already sick, our guide to taking a child’s temperature covers thermometers by age and when to call the pediatrician.
Quick answers
Is 62% alcohol enough?
Yes, by CDC’s line. CDC says to use a hand sanitizer with at least 60% alcohol, so 62% or 70% clears it. Then check the bottle on FDA’s do-not-use list. [S1] [S6]
Does sanitizer work on norovirus?
Not as well as soap. CDC says soap and water are more effective than sanitizer at removing certain germs, including norovirus. [S1]
Should I rinse my hands after using sanitizer?
No. CDC and FDA say not to rinse or wipe it off before it’s dry. Let it dry on your hands. [S1] [S4]
Is warm water better for washing?
CDC says warm and cold water remove the same number of germs. Use whichever you like. [S3]
Can a sanitizer have methanol even if the label doesn’t say so?
Yes. FDA says that in most cases methanol doesn’t appear on the label of contaminated products. That’s why FDA asks people to check its list. [S7] [S4]
Are products ranked here?
No. This guide explains published CDC and FDA information. It doesn’t rank or endorse any hand sanitizer or soap, and no products were tested for it.
Sources
CDC and FDA pages checked October 30, 2026. Recommendations here are our editorial reading of those pages; no hands-on results are claimed.
- S1 · CDC Clean Hands: Hand Sanitizer Guidelines and Recommendations (no page date shown)
- S2 · CDC Clean Hands: About Handwashing (Feb 16, 2024)
- S3 · CDC Clean Hands: Hand Hygiene Frequently Asked Questions (Mar 14, 2024)
- S4 · FDA Consumer Update: Safely Using Hand Sanitizer (Content current as of Apr 12, 2023)
- S5 · FDA Drug Safety Communication: FDA warns that vapors from alcohol-based hand sanitizers can have side effects (Content current as of Jun 16, 2021)
- S6 · FDA: FDA updates on hand sanitizers consumers should not use (Content current as of Apr 2, 2026)
- S7 · FDA press announcement: alcohol-based hand sanitizers from Mexico placed on import alert (Jan 26, 2021)